Opening a PDF file directly in Excel isn’t possible because Excel does not support PDF as a native file format. However, you can import data from a PDF into Excel by using Excel’s built-in data import tools. This allows you to extract tables and structured data from PDF documents and convert them into editable Excel sheets. To do this, go to the Data tab in Excel, choose the option to get data from a file, and select your PDF. Excel will then analyze the PDF and let you select the data tables you want to import.